• There are implications from this study by First the erythroc

  2018-10-30

  

  There are implications from this study by . First the erythrocyte, because of its unique glucose-sensitive mechanism of vitamin C uptake, may be more susceptible to intracellular ascorbate deficiency than other cell types in which ascorbate is taken up directly. Second, erythrocyte ascorbate deficie

• luciferin In keeping with a previous report in out

  2018-10-30

  

  In keeping with a previous report in 842 out-patients with stable cardiovascular disease (Parker et al., 2009), t-ucMGP correlated positively with eGFR. t-ucMGP, in the literature often referred to as ucMGP, predominantly consists of phosphorylated MGP and at variance with dp-ucMGP is not a biomarke

• Disclosure br Many lines of

  2018-10-30

  

  Disclosure Many lines of evidence have established that chronic kidney disease (CKD) is associated with a substantially increased risk of cardiovascular disease (CVD) (). In the majority of cases, the risk of CVD exceeds the risk of progression to end-stage kidney disease. Consequently, the “holy

• When untargeted analysis is considered pharmacometabolomics

  2018-10-30

  

  When untargeted analysis is considered, pharmacometabolomics also serves as a tool to shape hypothesis, as multiple analytes are quantified simultaneously and pharmacometabolomic modeling appears not to be limited by prior understanding or hypotheses. Hence, pharmacometabolomic modeling can be a pow

• Our study of C adds cogent support to

  2018-10-30

  

  Our study of C5 adds cogent support to more circumstantial evidence that has accumulated that a major, and not minor, function of DNA2 both in yeast and human is to participate in the protection, remodeling and restart of stalled replication forks. We first reported this when we showed, using 2D gel

• Despite its description over years

  2018-10-30

  

  Despite its description over 100years ago by German psychiatrist Alois Alzheimer, there has been little effective translation of insights on Alzheimer\'s disease (AD) pathobiology into effective treatments. As of 2015, roughly 50 million people globally — most over the age of 65years — have dementia

• In parallel with drug monitoring disease

  2018-10-29

  

  In parallel with drug monitoring, disease monitoring through non-invasive biomarkers plays an important role in IBD patients, as it allows an assessment of the inflammatory burden without the risks involved in colonoscopy-related procedures. Calprotectin constitutes up to 60% of the cytosolic protei

• br Conflict of Interest br Author Contributions br Acknowled

  2018-10-29

  

  Conflict of Interest Author Contributions Acknowledgements Introduction Previous studies suggest that impaired glucose regulation may be associated with cancer incidence or cancer-related death. This association was found among patients with diabetes mellitus (Hirakawa et al., 2012; Jee

• br Mass spectrometry data analysis The

  2018-10-29

  

  Mass spectrometry data analysis The workflow followed in the analysis and identification of proteins using Proteome Discoverer (PD) version 1.4.1.14 is shown in Fig. 1. Each of the raw files acquired from Orbitrap Velos Pro Mass Spectrometer were searched against the complete proteome of Aspergil

• br Materials and methods br

  2018-10-29

  

  Materials and methods Brief discussion Indicative peptide stereochemistries are shown in Fig. 1. In the absence of second shell O atoms, the native peptide, 3GSO_P, is under-coordinated in respect to the reference (also see Fig. 3b) and may not be differentiated from the other peptides exhibit

• NMR data were acquired on

  2018-10-29

  

  NMR data were acquired on Bruker AVANCE III HD 600MHz, AVANCE III HD 700MHz, and AVANCE III HD 800MHz spectrometers, each equipped with a cryogenic probe. NMR experiments used are summarized in Table 1. Experimental design, materials and methods Acknowledgments This work was supported by the

• br Specifications Table br Value of the data

  2018-10-29

  

  Specifications Table Value of the data Data Data shows increase in gene expression in ischemic muscles than healthy muscles upon direct administration of pDNA or pDNA/Pluronic (Fig. 2). The gene expression colocalized with inflammatory Tubastatin A (MØs) and the spread of overall GFP expre

• br Experimental design The dataset presented here

  2018-10-29

  

  Experimental design The dataset presented here was obtained from using the label-free proteomic analysis of three different strains of Prototheca species, P. zopfii genotype 1, genotype 2 and P. blaschkeae representing non-infectious, infectious and moderately infectious strains, respectively. In

• The diagnosis of pre eclampsia requires not

  2018-10-29

  

  The diagnosis of pre-eclampsia requires not only skilled health providers, but accurate medical devices that are appropriate for target settings, enabling users to identify pre-eclamptic women when the condition can be managed. In low- and middle-income countries (LMICs) access to the types of medic

• Recent research has highlighted the role of callous unemotio

  2018-10-29

  

  Recent research has highlighted the role of callous-unemotional (CU) traits, characterised by a lack of guilt, remorse and empathy, in increased risk for persistent antisocial behaviour and adult psychopathy (Barry et al., 2000; Frick et al., 2003; Viding, 2004; Frick and White, 2008; Frick et al.,

11566 records 761/772 page Previous Next First page 上5页 761762763764765 下5页 Last page